Retigel 0.05 % Topical Gel: View Uses, Side Effects, Price and Substitutes | 1mg (2025)

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Written By

Dr. Anuj Saini

MMST, MBBS

Reviewed By

Dr. Varun Gupta

MD Pharmacology, MBBS

Last updated

18 Feb 2025 | 11:20 AM (IST)

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Marketer

Oriental Pharma

SALT COMPOSITION

Isotretinoin (0.05% w/w)

Storage

Store below 30°C

Product introduction

Retigel 0.05 % Topical Gel belongs to a group of medicines known as retinoids that are used to treat severe acne, which occur as pimples, in adults and adolescents from 12 years of age only after puberty. This medicine is for patients whose acne has not responded to other treatments.

Retigel 0.05 % Topical Gel reduces excessive oil production of the skin. Ideally, a pinpoint application at night time is recommended for a duration as prescribed by the doctor. The dose and duration will depend on what you are being treated for. You should normally wash and dry the affected area before applying a thin layer of the medicine usually once a day at bedtime. Follow your doctor’s instructions. Do not apply it to damaged or broken skin and avoid contact with your mouth, eyes, and nose. It may take several weeks for your symptoms to improve but keep using it regularly to get the most benefit. If you notice no improvement after a few weeks, see your doctor again.

The most common side effects include itching, stinging, peeling, and redness of the skin. They are not usually serious and often disappear after getting used to the cream but, if they bother you or do not go away, tell your doctor. You may need to apply smaller amounts or use it less often. Serious side effects are rare.

Retigel 0.05 % Topical Gel may make you more sensitive to sunlight so you should limit exposure to the sun if possible. Drink plenty of water and use moisturizer as it may lead to dryness of the mouth, lips, and eyes. It may make your skin more fragile. It is advised, not to have any waxing (hair removal), or laser treatments during treatment. This medicine may lead to birth defects, do consult your doctor if you are pregnant or planning to get pregnant.

Uses of Retigel Gel

  • Treatment of Acne

Benefits of Retigel Gel

In Treatment of Acne

Retigel 0.05 % Topical Gel helps treat acne by reducing the production of sebum (a natural substance) that causes acne. This kills acne-causing bacteria and prevents spots or pimples from appearing. It usually takes a few weeks to have a noticeable effect so keep taking it even if it appears not to be working. Sometimes acne may get worse before it gets better, however, with proper use, your skin will get clearer. This medicine will help improve your mood and uplift your confidence as your skin becomes acne-free.

Side effects of Retigel Gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Retigel

  • Application site reactions (burning, irritation, itching and redness)
  • Dry skin
  • Rash

How to use Retigel Gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

How Retigel Gel works

Retigel 0.05 % Topical Gel is a derivative of vitamin A. It acts on glands (sebaceous) on your skin to reduce the production of a natural substance (sebum) that causes acne. Also, the controlled sebum production kills acne-causing bacteria. It also works as an anti-inflammatory to decrease inflammation (redness and swelling).

Safety advice

No interaction found/established

Pregnancy

UNSAFE

Retigel 0.05 % Topical Gel is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.

Breast feeding

CONSULT YOUR DOCTOR

Retigel 0.05 % Topical Gel is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.

Driving

No interaction found/established

Kidney

No interaction found/established

Liver

No interaction found/established

What if you forget to take Retigel Gel?

If you miss a dose of Retigel 0.05 % Topical Gel, apply it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Retigel 0.05 % Topical Gel

₹192/Gel

Sotret Gel

Sun Pharmaceutical Industries Ltd

₹238/gel

19% costlier

Acno Gel

Ajanta Pharma Ltd

₹95.88/gel

52% cheaper

Istra 0.05% Gel

Carlton Dermatology

₹169/gel

16% cheaper

Sotret Gel

Sun Pharmaceutical Industries Ltd

₹92.76/gel

54% cheaper

Isotroin 0.05% Gel

Cipla Ltd

₹94.92/gel

53% cheaper

Quick tips

  • You have been prescribed Retigel 0.05 % Topical Gel for the treatment of acne.
  • Clean the area to be treated with water and a non-medicated soap, and let it dry for 20-30 minutes before applying Retigel 0.05 % Topical Gel.
  • It may increase the severity of the lesions in the first few weeks of use. Continue using it as prescribed by your doctor.
  • It may cause a stinging sensation or a feeling of warmth when you first start using it. Inform your doctor if this persists.
  • Avoid exposure to sunlight while using it as it increases the sensitivity of your skin. Use protective measures such as sun-cream or protective clothing.
  • Avoid face waxing and laser treatment while using this medicine as it makes your skin more fragile.
  • Do not use Retigel 0.05 % Topical Gel if you are pregnant or breastfeeding.

  • Inform your doctor if excessive skin dryness or skin sensitivity take place.

Fact Box

Chemical Class

Retinoid

Habit Forming

No

Therapeutic Class

DERMA

Action Class

Retinoids- First generation

Patient concerns

Please suggest better treatment for acne and piles

Dr. Atul Jain

Dermatology

For acne-use Nadoxin gel at night over acne For piles-pls visit near general surgeon

MORE

This Prescription is given by A Dermatologist!! Please check it For my redness on skin

Dr. Atula Gupta

Dermatology

These medicines for acne

MORE

I have acne . I started having them from last 5 yrs . Is drinking warm water a good solution ? Pls suggest me a good acne soap

Dr. Atula Gupta

Dermatology

D acne face wash

MORE

hello ma, im suffering from severe acne im under medication from last two months, im taking resoten capsules and aapplying tretinoin cream at night, but still my acne are comming vigorously what will i do please tell

Dr. Atul Jain

Dermatology

Few acne can come

MORE

Dear sir i want to any cream for removing the acne pimples from the face

Dr. Sunil Sekhri

Diabetology

First acne severity need to be assessed in the clinic. I give tailor made treatment to my Acne patients

MORE

I have lot of pimple marks on face and And still pimple appear on face

Dr. Saurav Arora

Homeopathy

Please send pictures of acne

MORE

Acne Problems Pimples Problem My skin is oily please suggestion. Treatment.

Dr. Saurav Arora

Homeopathy

Please send pictures of acne

MORE

I have an acne on face and it is painning and it has been from 7 months so what should I do it to prevent it

Dr. Atul Jain

Dermatology

Plz visit for such acne

MORE

FAQs

What are the precautions that I should follow while using Retigel 0.05 % Topical Gel?

Avoid any contact of Retigel 0.05 % Topical Gel with mouth, eyes, lips, mucous membranes (such as inside of mouth), and wounded skin. In case of accidental contact, rinse well with water. Do not let the medicine accumulate in skin folds. Retigel 0.05 % Topical Gel may also cause increased sensitivity to sunlight so avoid or minimize deliberate or prolonged exposure to sunlight or sunlamps. If sun exposure cannot be avoided, use sunscreen.

I just had a cosmetic treatment. Can I use Retigel 0.05 % Topical Gel on that part of the skin?

Don’t use Retigel 0.05 % Topical Gel on skin that has recently had cosmetic treatment such as depilation, chemical hair treatment, chemical peel, dermabrasion, or laser resurfacing. You should allow your skin to heal after any treatment before using Retigel 0.05 % Topical Gel. However, if not sure, consult your doctor.

I have stopped using Retigel 0.05 % Topical Gel. Can I now plan my pregnancy?

Consult your doctor before planning a pregnancy. Usually, it is advised to wait for about 1 month after stopping Retigel 0.05 % Topical Gel before you plan your pregnancy. This is done to avoid any harm to your unborn baby because of the medicine.

Can Retigel 0.05 % Topical Gel be used in children?

Retigel 0.05 % Topical Gel gel is used to treat mild to moderate acne in teenagers and adults. It should not be used in children before puberty or under the age of 12.

What if I use too much Retigel 0.05 % Topical Gel?

If you use too much Retigel 0.05 % Topical Gel gel or use it more often than recommended, it may make your skin red or irritated. If this happens, use the gel less often or stop using it for a few days.

Can I donate blood while using Retigel 0.05 % Topical Gel?

Do not donate blood while using Retigel 0.05 % Topical Gel gel and for at least 1 month after stopping it. If your blood is given to a pregnant woman, it may harm her unborn baby.

How do I use Retigel 0.05 % Topical Gel on my face?

Always wash and dry your skin, and completely remove any make-up before applying the gel. Use your fingertips to apply a thin layer of the gel to all areas of skin that have acne and not just each spot. Try not to use too much, especially where the gel could run into your eyes or build up in folds of skin. Using more gel will not make your spots clear up more quickly. Do not use Retigel 0.05 % Topical Gel gel on irritated areas of skin, for example, cuts, burns, or sunburn as it can make the irritation worse.

How long does it take for Retigel 0.05 % Topical Gel to start working?

The acne may get worse at the beginning of the treatment with Retigel 0.05 % Topical Gel gel. But, it normally improves after 6 to 8 weeks.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Robertson DB, Maibach HI. Dermatologic Pharmacology. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1056.

  2. Burkhart C, Morrell D, Goldsmith L. Dermatological Pharmacology. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1812.

  3. Sardana K, Madan A. How to Treat Acne. Sardana K, editor. In: Clinical Approach to Acne Vulgaris. 1st ed. New Delhi: CBS Publishers & Distributors Pvt. Ltd.; 2015. pp. 64-67.

  4. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 745-47.

  5. ScienceDirect. Isotretinoin. [Accessed 03 Apr. 2019] (online) Available from:Retigel 0.05 % Topical Gel: View Uses, Side Effects, Price and Substitutes | 1mg (5)

  6. Central Drugs Standard Control Organisation (CDSCO). [Accessed 03 Apr. 2019] (online) Available from:Retigel 0.05 % Topical Gel: View Uses, Side Effects, Price and Substitutes | 1mg (6)

  7. Central Drugs Standard Control Organisation. Isotretinoin. [Accessed 05 Jul. 2023]. (online) Available from: Retigel 0.05 % Topical Gel: View Uses, Side Effects, Price and Substitutes | 1mg (7)

  8. Isotretinoin [Consumer Medicine Information]. Auckland, New Zealand: GlaxoSmithKline NZ Limited; 2013. [Accessed 05 Jul. 2023]. (online) Available from:Retigel 0.05 % Topical Gel: View Uses, Side Effects, Price and Substitutes | 1mg (8)

  9. Isotretinoin [Product Information]. Dhaka, Bangladesh: Incepta Pharmaceuticals Ltd. [Accessed 05 Jul. 2023]. (online) Available from:Retigel 0.05 % Topical Gel: View Uses, Side Effects, Price and Substitutes | 1mg (9)

Marketer details

Name: Oriental Pharma

Address: A-294, Okhla Phase-1, New Delhi-110 020

Country of origin: India

Lab tests offered by us

Retigel 0.05 % Topical Gel: View Uses, Side Effects, Price and Substitutes | 1mg (10)

Related/Popular tests

  • CBC (Complete Blood Count)
  • FBS (Fasting Blood Sugar)
  • HbA1c (Glycosylated Hemoglobin)
  • PPBS (Postprandial Blood Sugar)
  • Lipid Profile
  • Vitamin D (25-Hydroxy)
  • Coronavirus Covid -19 test- RT PCR
  • LFT (Liver Function Test)
  • KFT (Kidney Function Test)
  • TSH (Thyroid Stimulating Hormone) Ultrasensitive
  • ESR (Erythrocyte Sedimentation Rate)
  • Uric Acid
  • Vitamin B12
  • CRP (C-Reactive Protein), Quantitative
  • Urine C/S (Urine Culture and Sensitivity)
  • Serum Electrolytes
  • Serum Calcium
  • Serum Creatinine
  • KFT with Electrolytes (Kidney Function Test with Electrolytes)
  • Cholesterol - Total
  • Hb (Hemoglobin)

192

Inclusive of all taxes

MRP₹200 4% OFF

20.0 gm in 1 tube

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Retigel 0.05 % Topical Gel: View Uses, Side Effects, Price and Substitutes | 1mg (2025)
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