Bug Off Garlic Granules for Dogs (2024)

Garlic: The Science and Therapeutic Application of Allium sativum L. and Related Species Second Ed.

Edited By:

Heinrich P. Koch, Ph.D., M.Pharm.
Professor of Pharmaceutical Chemistry and Biopharmaceutics, University of Vienna, Vienna, Austria

Larry D. Lawson, Ph.D.
Research Scientist, Murdock Madaus Schwabe Group, Springvale, Utah

Published By:

Williams & Wilkens, Baltimore, Maryland, 1996.

Garlic Studies

Insecticidal and Repellent Effects

Hills, L.D. (1972) Will garlic replace DDT? Org. Garden. Farm (Sept.)

Population Studies - Low cancer rates associated with regular garlic consumption.

Dorant, E., van den Brandt. P.A., and Goldbohm, R.A. (1994b) A prospective cohort study on Allium vegetable consumption, garlic supplement use, and the risk of lung carcinoma in the Netherlands. Cancer Res. 54:6148-6153.

Yang, C.S., Wang, Z.Y., and Hong, J.Y., (1994b) Inhibition of tumorigenesis by chemicals from garlic and tea. In: Advances in experimental medicine and biology: diet and cancer: markers, prevention, and treatment. M.M. Jacobs, ed. Plenum, New York, pp. 113-122. Chem. Abst. 122 (1995) 22 889.

Caldwell, D.R. and Danzer, C.J. (1988) Effects of allyl sulfides on the growth of predominant gut anaerobes. Curr. Microbiol. 16:237-241. Chem. Abst. 108 (1988) 146 953.

Abdullah, T.H., Kandil, O., Elkadi, A., and Carter, J. (1988) Garlic revisited: therapeutic for the major diseases of our times? J. Nat. Med. Assoc. 80:439-445. Chem. Abst. 109 (1988) 21 973. Int. Pharm. Abst. 26 (1989) 2286.

Immune Stimulant Effects of Garlic: Animal and In Vitro Studies

Nakata, T. (1973) Effects of fresh garlic extract on tumor growth. Nippon Eiseigaku Zasshi (Jap. J. Hyg.) 27:538-543. Chem. Abst. 79 (1973) 111 680 (Japanese).

Nakata, T., and Fujiwara, M. (1975) Adjuvent action of garlic sugar solu-tion in animals immunized with Ehrlich ascites tumor cells attenuated with allicin. Gann 66:417-419.

Weisberger, A.S., and Pensky, J. (1957) Tumor-inhibiting effects derived from an active principle of garlic (Allium sativum). Science 126:1112-1114.

Effect of garlic on tumors in mice and rats

Kametani, T., f*ckumoto, K., and Umezawa, O. (1959) Studies on anticancer agents. I. Synthesis of various alkyl thiosulfinates and tumor-inhibiting effect. Yakugaku Kenkyu (Jap. J. Pharm. Chem.) 31:60-74. Chem. Abst. 54 (1960) 11 018 (Japanese).

Hirsch, A.F., Piantadosi, C., and Irvin, J.L. (1965) Potential anticancer agents. II. The synthesis of some nitrogen mustard containing sulfones and thiosulfinates. J. Med. Chem. 8:10-14. Chem. Abst. 62 (1965) 5215.

Zhou, J., Qi, R., and Zhang, M. (1988) Growth suppression of human leukemic cells in vitro by garlicin (ethyl ethanethiosulfinate). Shandong Yike Daxue Xuebao 26:43-47. Chem. Abst. 110 (1989)

Cheng, H.H. and Tung, T.C. (1981) Effect of allithiamine on sarcoma-180 tumor growth in mice. Taiwan I Hsuch Hui Tsa Chih 80:385-393. Chem. Abst. 95 (1981) 197 366 (Chinese).

Di Paolo, J.A. and Carruthers, C. (1960) The effect of allicin from garlic on tumor growth. Cancer Res. 20:431-434. Chem. Abst. 55 (1961) 3844.

Kimura, Y. and Yamamoto, K. (1964) Cytological effect of chemicals on tumors: influence of crude extracts from garlic and some related species on MTK-sarcoma III. Gann 55:325-329. Chem. Abst. 63 (1965) 1089.

Fujiwara, M. and Natata, T. (1967) Induction of tumor immunity with tumor cells treated with extract of garlic (Allium sativum). Nature 216:83-84.

Aboul-Enein, A.M. (1986) Inhibition of tumor growth with possible immunity by Egyptian garlic extracts. Nahrung 30:161-169

Lau, B.H.S., Woolley, J.L., Marsh, C.L., Barker, G.R., Koobs, D.H., and Torrey, R.R. (1986a) Superiority of intralesional immunotherapy with Corynebacterium parvum and Allium sativum in control of murine transitional cell carcinoma. J. Urol. 136:701-705.

Antioxidant Effects

Jacob, R., Isensee, H., Rietz, B., Makdessi, S., and Sweiden, H. (1993a) Cardioprotection by dietary interventions in animal experiments: effect of garlic and various dietary oils under the conditions of experimental infarction. Pharm. Pharmacol. Lett. 3:124-127. Chem. Abst. 123. (1994) 162 425.

Torok, B., Belagyi, J., Rietz, B., and Jacob, R. (1994) Effectiveness of garlic on the radical activity in radical generating systems.

Antidote for Heavy Metal Poisoning and Other Toxins

Hanafy, M.S.M., Shalaby, S.M., El Fouly, M.A.A., El Aziz, M.I.A., and Soliman, F.A. (1994) Effect of garlic on lead contents in chicken tissues. Dtsch. Tieraeztl. Wochenschr. 101:157-158.

Cha, C.W. (1987) A study on the effect of garlic to the heavy metal poisoning of rats. J. Korean Med. Sci. 2:213-223. Chem. Abst. 109 (1988) 18 322.

Spot-On Flea & Tick Toxicity:

75,000 Adverse Reactions Reported (Millions Probably Unreported)

National Pet Poison Hotline Report Incidents at 800-858-7378

How to tell if your pet has been poisoned

Symptoms of poisoning by flea/tick treatments may
include salivating, dilated pupils, tremors, vomiting,
hiding, shivering, convulsions, and skin irritation.

What to do if your pet has been poisoned

If you suspect your pet may have suffered negative
health effects as a result of a flea product,
consult with your veterinarian immediately.
Be sure to report all such incidents to the
EPA's National Pesticide Telecommunications Network
at 800-858-7378.

"Spot-On" Flea & Tick Products Alleged to Cause Serious Harm to Dogs and Cats

-- Pet Pharmaceutical Industry Under Fire
in Multiple New Jersey Class Action Lawsuits --

NEWARK, N.J., Dec. 8, 2011 /PRNewswire via COMTEX/ — There is a growing sense of moral outrage and alarming statistics from consumers and pet advocates alike after over 75,000 complaints about the products have been reported to the EPA and nothing has been done to change the advertising, marketing or labeling of the products to alert pet owners of the possible serious side-effects. What's chilling is that those numbers only reflect what has been reported, the actual number of incidents may be much, much higher.

http://www.humanesociety.org/animals/resources/tips /flea_tick_OTC_pet_products.html